Transient absolute robustness in stochastic biochemical networks
نویسندگان
چکیده
منابع مشابه
Transient absolute robustness in stochastic biochemical networks.
Absolute robustness allows biochemical networks to sustain a consistent steady-state output in the face of protein concentration variability from cell to cell. This property is structural and can be determined from the topology of the network alone regardless of rate parameters. An important question regarding these systems is the effect of discrete biochemical noise in the dynamical behaviour....
متن کاملStochastic analysis of biochemical reaction networks with absolute concentration robustness.
It has recently been shown that structural conditions on the reaction network, rather than a 'fine-tuning' of system parameters, often suffice to impart 'absolute concentration robustness' (ACR) on a wide class of biologically relevant, deterministically modelled mass-action systems. We show here that fundamentally different conclusions about the long-term behaviour of such systems are reached ...
متن کاملSupporting Online Material for: Stochastic analysis of biochemical reaction networks with absolute concentration robustness
2 Background, terminology, and notation 2 2.1 Chemical reaction networks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.2 Deterministic chemical reaction systems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.2.1 Absolute concentration robustness . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2.2.2 Reformulation of equ...
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ژورنال
عنوان ژورنال: Journal of The Royal Society Interface
سال: 2016
ISSN: 1742-5689,1742-5662
DOI: 10.1098/rsif.2016.0475